Health
UNILAG Researchers Collaboration With Global Consortium Unravels Novel Parkinson’s Genetics Risk Factor In Africans and African Admixed Populations

Photo : ▪︎Prof. Njideka Okubadejo, Department of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Lagos.
Akoka, Lagos – Researchers from the University of Lagos are key collaborators in the Global Parkinson’s Genetics Program (GP2) that uncovered a genetic variant that increases the risk of Parkinson’s Disease (PD) in Africans and African admixed populations.
The research finding was the result of teamwork by an international team including the Nigeria Parkinson Disease Research (NPDR) network, the International Parkinson’s Disease Genomics Consortium (IPDGC)-Africa, University College London, the National Institutes of Health (NIH) in
the US, and 23andMe.
The study was funded by the Michael J Fix foundation for Parkinson’s research and GP2.
The NPDR network and UNILAG team are led by a Professor of Neurology in the Department of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Lagos, Professor Njideka Okubadejo who acknowledges the crucial role that the supportive research environment at the
university and the commitment of the national and international partners played in the success of the team.
She said “This GBA1 result is a step toward that future, where the research field is
prioritizing, learning from, and treating all people with Parkinson’s disease.”
Other members of the UNILAG team collaborating with the Global consortium (GP2) include: Dr. Oluwadamilola ‘Lara’ Ojo (Associate Professor and Site Lead Investigator, Faculty of
Clinical Sciences (FCS);
Dr. Osigwe Agabi (FCS);
Prof. Francis Ojini (FCS)
and Dr. Ismail Ishola (Faculty of Basic Medical Sciences (FBMS).
Others are Dr. Francisca Nwaokorie (Associate Professor, FBMS); Mr. Roosevelt Anyanwu (Central Research Laboratory CMUL), and Dr. Arinola Sanyaolu (FBMS).
The variant on the GBA1 gene was identified by the GP2 researchers as part of efforts to galvanize international/collaborative research into the genetics of Parkinson’s Disease (PD) as well as revolutionize treatment for the African and African admixed population.
While more research is needed to define the exact mechanism of the new variant, initial findings also suggest that like prior mutations in GBA1, this variant results in lowered activity of the glucocerebrosidase (GCase) enzyme.
The Global Parkinson’s Genetics Program (GP2) is a resource programme of the Aligning Science Across Parkinson’s (ASAP) initiative, it is funded by the Sergey Brin Family Foundation and implemented by The Michael J. Fox Foundation for Parkinson’s Research (MJFF).
The Aligning Science Across Parkinson’s (ASAP) launched GP2 in 2019 to follow up on previous funding efforts from the Michael J. Fox Foundation for Parkinson’s Research (MJFF) with a view to expanding global genetics study in populations traditionally underrepresented in research.
Till date, the GP2 is partnering with over 140 cohorts from around the world, assembling,
generating and sharing data to uncover novel insights and similarities in Parkinson’s Disease (PD).
The Vice-Chancellor, University of Lagos, Professor Folasade Ogunsola, on behalf of the University Senate, Management, Staff and Students, congratulates the UNILAG team on the GP2 project for their impact in the latest discovery.
Professor Ogunsola says the UNILAG team’s input and impact on the GP2 further accentuates the university’s fast migration into a Future-Ready institution with imprints in various fields including
Science.
Health
JUST IN: Ogun confirms Lassa fever outbreak as NYSC member dies

A 25-year-old member of the National Youth Service Corp (NYSC), has reportedly died of Lassa fever at a secondary health facility in ljebu North Local Government Area of Ogun State.
It wwas learnt that the female corp member who fell sick while in Ondo State, was brought to the health facility last Tuesday and later died same day.
This was contained in a statement signed by the Commissioner for Health, Tomi Coker, on Wednesday.
Coker also confirmed the outbreak of Lassa fever in the state.
The statement reads, “Ogun State has confirmed a case of Lassa Fever and as such declared Lassa fever outbreak.
“The index case is a 25-year-old female National Youth Corp member who fell sick while in Ondo State and was brought to on of our secondary health facility in ljebu North LGA on 18th March 2025 and later died same day.
“ Lassa fever is a viral Haemorrhagic disease that presents with High grade fever, Headache, General body weakness, Sore throat, Muscle pain, Cough, Nausea, Vomiting, Diarrhoea, Chest pain and Unexplained bleeding from the ears, eyes, nose, mouth and other body openings.
”Coker urged members of the community to report to the hospital if any of the listed symptoms is noticed.
“We implore members of the community to promptly report to the hospital if they notice any of these symptoms.
Any case of febrile illness that has not responded to 48 hours use of anti-malaria or antibiotics should raise an index of suspicion for Lassa fever!
“We implore all Health facilities in Ogun State, public and private, to step up Infection Prevention and Control measures and to encourage compliance by all health facility staff.“
Healthcare worker that suspects Lassa fever in a patient, are advised to call their local government disease surveillance and notification officer (LGA DSNO) whose numbers are placed in our health facilities or call State Disease surveillance and Notification Officer (0703-421-4893) or State Epidemiologist (0808-425-0881),” she added.
The commissioner, however reiterated the Governor Dapo Abiodun-led administration’s dedication to protecting the health of the citizens through continuous surveillance and prompt response to infectious diseases.
She added that the ministry in collaboration with the Rapid Response Team at ljebu North East is keeping the situation under control with enhanced surveillance and community engagement and mobilization for effective response.
Health
JUST IN: NAFDAC goes digital in fight against fake pharmaceutical products

The National Agency for Food and Drug Administration and Control, NAFDAC, has gone digital in its efforts to rid the country of substandard and falsified pharmaceutical products.
During a two-day workshop and training session in Port Harcourt, Rivers State, on Wednesday, NAFDAC introduced an app, Greenbook, an online platform for identifying the source of a product.
The Greenbook allows consumers to enter the product name, brand name, or registration number to search for information about its registration status.
If the product is listed in the Greenbook, it signifies that it has been registered by NAFDAC and is considered authentic.
The app serves as a tool to help consumers identify and avoid potentially fake or substandard products.
The Director-General of NAFDAC, Prof. Mojisola Adeyeye, speaking at the workshop in Port Harcourt, stated that these fake products are “produced by our greedy businessmen and their international collaborators to get rich or make money,” describing it as the worst form of inhumanity of man to his fellow men.
Prof. Adeyeye, who was represented by the Director of the Post-Marketing Surveillance Directorate, NAFDAC, Fraden Bitrus, noted that the agency has, over the years, deployed various measures to combat falsified products.
She expressed concern that counterfeiters have adopted increasingly sophisticated methods to advance their trade but assured that NAFDAC “is poised to use technologies and modern means to mitigate the activities of counterfeiters, hence the need for stakeholder sensitisation.”
She added that the workshop aims to educate stakeholders and provide hands-on training on the NAFDAC Greenbook, the Traceability Regulation 2024, and the Paediatric Regulation 2024, ensuring that both the regulator and the regulated are aligned in the fight against substandard and falsified medical products.
Prof. Adeyeye revealed that the project is being implemented in phases, initially used for COVID-19 vaccine distribution as a pilot project, which yielded highly effective results.
She noted, “Within 24 hours, batches of substandard or defective vaccines distributed in the country were traced and recalled.”
She further stated, “We have implemented it for commodities in public health, such as antimalarial and narcotic products.
Over time, we will extend it to other products. Please note that with this technology, stakeholders can detect and reject SF products before they enter the supply chain.”
She called on all stakeholders in the healthcare sector to support these initiatives to combat fake products and ensure the availability of quality, safe, and efficacious medical products for the people of Nigeria.
Health
IPOB to NAFDAC: Return seized goods from Onitsha drug market

The Indigenous People of Biafra (IPOB) has called on the National Agency for Food and Drug Administration and Control (NAFDAC) to return goods seized from traders at Ogbo Ogwu Drug Market in Onitsha, Anambra State.
In a statement issued by IPOB’s Media and Publicity Secretary, Comrade Emma Powerful, the group alleged that NAFDAC officials conducted a midnight raid on the market, blocking CCTV cameras, breaking into shops, and confiscating goods under the claim of targeting fake drugs.
IPOB criticized the method of the operation, questioning the agency’s approach and transparency.
While IPOB reaffirmed its stance against the sale of counterfeit drugs, it raised concerns over the alleged seizure of traders’ goods in their absence, the blocking of surveillance cameras, and the lack of evidence proving that all confiscated products were counterfeit.
The group posed several questions to NAFDAC, including: Why was the operation conducted at midnight? Why were CCTV cameras blocked?
Where is the evidence that the confiscated drugs were fake? Why was the entire market sealed, affecting both innocent and guilty traders?
IPOB urged NAFDAC to adopt a more professional and transparent approach to combating fake drugs, suggesting that the agency establish permanent offices in drug markets to ensure proper regulation rather than conducting surprise raids.
The statement also called for collaboration between NAFDAC and the Anambra State Government to relocate the drug market to the new Oba Drug Market, ensuring that only licensed and certified dealers are allowed to operate.
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