Health
UNILAG Researchers Collaboration With Global Consortium Unravels Novel Parkinson’s Genetics Risk Factor In Africans and African Admixed Populations
Photo : ▪︎Prof. Njideka Okubadejo, Department of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Lagos.
Akoka, Lagos – Researchers from the University of Lagos are key collaborators in the Global Parkinson’s Genetics Program (GP2) that uncovered a genetic variant that increases the risk of Parkinson’s Disease (PD) in Africans and African admixed populations.
The research finding was the result of teamwork by an international team including the Nigeria Parkinson Disease Research (NPDR) network, the International Parkinson’s Disease Genomics Consortium (IPDGC)-Africa, University College London, the National Institutes of Health (NIH) in
the US, and 23andMe.
The study was funded by the Michael J Fix foundation for Parkinson’s research and GP2.
The NPDR network and UNILAG team are led by a Professor of Neurology in the Department of Medicine, Faculty of Clinical Sciences, College of Medicine, University of Lagos, Professor Njideka Okubadejo who acknowledges the crucial role that the supportive research environment at the
university and the commitment of the national and international partners played in the success of the team.
She said “This GBA1 result is a step toward that future, where the research field is
prioritizing, learning from, and treating all people with Parkinson’s disease.”
Other members of the UNILAG team collaborating with the Global consortium (GP2) include: Dr. Oluwadamilola ‘Lara’ Ojo (Associate Professor and Site Lead Investigator, Faculty of
Clinical Sciences (FCS);
Dr. Osigwe Agabi (FCS);
Prof. Francis Ojini (FCS)
and Dr. Ismail Ishola (Faculty of Basic Medical Sciences (FBMS).
Others are Dr. Francisca Nwaokorie (Associate Professor, FBMS); Mr. Roosevelt Anyanwu (Central Research Laboratory CMUL), and Dr. Arinola Sanyaolu (FBMS).
The variant on the GBA1 gene was identified by the GP2 researchers as part of efforts to galvanize international/collaborative research into the genetics of Parkinson’s Disease (PD) as well as revolutionize treatment for the African and African admixed population.
While more research is needed to define the exact mechanism of the new variant, initial findings also suggest that like prior mutations in GBA1, this variant results in lowered activity of the glucocerebrosidase (GCase) enzyme.
The Global Parkinson’s Genetics Program (GP2) is a resource programme of the Aligning Science Across Parkinson’s (ASAP) initiative, it is funded by the Sergey Brin Family Foundation and implemented by The Michael J. Fox Foundation for Parkinson’s Research (MJFF).
The Aligning Science Across Parkinson’s (ASAP) launched GP2 in 2019 to follow up on previous funding efforts from the Michael J. Fox Foundation for Parkinson’s Research (MJFF) with a view to expanding global genetics study in populations traditionally underrepresented in research.
Till date, the GP2 is partnering with over 140 cohorts from around the world, assembling,
generating and sharing data to uncover novel insights and similarities in Parkinson’s Disease (PD).
The Vice-Chancellor, University of Lagos, Professor Folasade Ogunsola, on behalf of the University Senate, Management, Staff and Students, congratulates the UNILAG team on the GP2 project for their impact in the latest discovery.
Professor Ogunsola says the UNILAG team’s input and impact on the GP2 further accentuates the university’s fast migration into a Future-Ready institution with imprints in various fields including
Science.
Health
WHO: United States membership withdrawal takes effect
Reacting to the development, WHO Director-General, Dr Tedros Adhanom Ghebreyesus, expressed regret over the decision and urged the United States to reconsider.
The United States’ withdrawal from the World Health Organisation (WHO) officially took effect on Thursday, exactly one year after President Donald Trump ordered the country to pull out of the global health body.
Under the terms governing WHO membership, a withdrawal becomes effective after a mandatory one-year notice period, which expired on Thursday 22 January, following the executive order signed by Trump shortly after he took office in 2025.
Although the agreement requires the United States to settle all outstanding financial obligations before withdrawal, that condition has not been met. However, the WHO has no legal mechanism to enforce payment or prevent a member state from exiting the organisation.
Reacting to the development, WHO Director-General, Dr Tedros Adhanom Ghebreyesus, expressed regret over the decision and urged the United States to reconsider.
“The withdrawal is a loss for the United States and also a loss for the rest of the world,” Tedros said, adding that the organisation remains open to the country’s return.
President Trump had justified the decision by accusing the WHO of mishandling the COVID-19 pandemic, which originated in Wuhan, China, as well as other global health emergencies.
He also cited the organisation’s alleged failure to implement necessary reforms and its inability to operate independently of political influence from member states.
Health
Obasanjo to champion Nigeria’s newborns health as 800 die Everyday
Speaking at a press conference in Abeokuta, Ogun State, ahead of the 57th Annual General Meeting and Scientific Conference of the association, Ekure lamented about Nigeria’s worsening child health indicators, warning that vaccine-preventable diseases, malnutrition and rising newborn deaths continue to claim thousands of young lives daily.
Image credit: Meta AI
The Paediatric Association of Nigeria (PAN) says that former President , Chief Olusegun Obasanjo, has accepted to be an advocate for children’s nutrition and healthcare in an efforts to reduce the high deaths rate amongst them.
“More than 800 Nigerian families lose a newborn everyday, despite the fact that most of the deaths are preventable,” said the PAN President, Dr Ekanem Ekure.
Speaking at a press conference in Abeokuta, Ogun State, ahead of the 57th Annual General Meeting and Scientific Conference of the association, Ekure lamented about Nigeria’s worsening child health indicators, warning that vaccine-preventable diseases, malnutrition and rising newborn deaths continue to claim thousands of young lives daily.
While visited former President Olusegun Obasanjo at his residential house in OOPL, the association demanded that he should an advocate for children’s nutrition. A tasked he greatly accepted.
He pledged to be an advocate of child healthcare and utilize his strength even though he doesn’t have children at hand anymore.
Ekure said Nigeria remained off track in achieving Sustainable Development Goal 3 (SDG-3), particularly in the areas of neonatal and under-five survival, describing the situation as a national emergency requiring urgent political, financial and technological intervention.
According to her, about 50 percent of child deaths in Nigeria are worsened by malnutrition, noting that poorly nourished children are far more likely to die from infections than healthy ones.
Ekure blamed vaccine hesitancy, misinformation, poverty, insecurity and weak health financing for Nigeria’s high burden of preventable child deaths, warning that the resurgence of diseases such as measles in some parts of the country mirrored global trends where immunisation rates have fallen.
Health
Money-for-marks scandal rocks Rivers State medical college
Oreh said, “The Rivers State Ministry of Health, and indeed the Rivers State Government, have zero tolerance for corruption in any shape or form.”
• Rivers State’s Commissioner for Health, Dr Adaeze Oreh
The Rivers State Government has ordered a full-scale investigation into allegations of extortion, including money-for-marks and the sale of examination papers, at the State College of Medical Sciences in Port Harcourt.
The State’s Commissioner for Health, Dr Adaeze Oreh, disclosed that following the allegations, the government has suspended the head of one of the departments linked to the alleged offences, although the specific department was not disclosed.
She also announced that a committee chaired by the Chief Medical Director of the Rivers State University Teaching Hospital had been constituted to thoroughly investigate the allegations.
Oreh said that the action followed a series of complaints against the institution, which also included allegations of students being compelled to pay for the approval of project topics.
Oreh said, “The Rivers State Ministry of Health, and indeed the Rivers State Government, have zero tolerance for corruption in any shape or form.”
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